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  VACCINE CONCERNS  

Are vaccines safe? is a question many parents ask. The purpose of this section is to help you find medically and scientifically accurate information about vaccines and immunizations to help you answer some of your questions. A great deal of information about vaccines is available today in print, through the media, and on the Internet. It is important for both patients and providers to have access to current research and be able to read about issues that affect health. However, not all the information you will find is accurate, and some statements may be misleading when taken out of context.

The disappearance of many vaccine-preventable childhood diseases has led some parents to question whether immunizations are still needed. In addition, some parents are concerned that vaccines may be the cause of conditions such as autism. These concerns have led some parents to delay or withhold vaccines for their children.

Here are some answers to questions asked by San Diego families about vaccines, with links to nationally respected immunization resources should you wish to look further. (You can also look in the Frequently Asked Questions section for additional information.)


Q: Why immunize?

A: Immunization provides protection against the risk of dangerous diseases. The protection provided by vaccines falls into three categories:

  • Protection against common infections, such as chickenpox and whooping cough
  • Protection against infections that are now at low levels but could easily reemerge. These include measles, mumps, rubella and Haemophilus Influenzae type b (Hib)
  • To prevent infections that are still common in other parts of the world, such as polio and diphtheria

(Atkinson, W. et al. Epidemiology and Prevention of Vaccine-Preventable Diseases, 6th Edition, Centers for Disease Control and Prevention, USDHHS, 2000)

Immunization has reduced most vaccine-preventable diseases to all-time lows in the U.S., but this is not true for all parts of the world. Many of the diseases that we never see are still common in other countries, and are only a plane ride away from our community and our families. Widespread immunization is the wall that stands between these diseases and their rapid spread through our population.

We immunize to protect our children and ourselves. While it may seem that the risk of getting any of these diseases is small, they still exist, and can infect anyone who is not protected. San Diego is one of the busiest ports of entry into the United States, with many millions of travelers and new residents entering the county every year. It attracts tourists, immigrants, students and members of the military from every corner of the globe, and anyone might unknowingly bring these diseases to a shopping center, school, or neighborhood near you.

We also immunize to protect those around us. There are some people who cannot be vaccinated because of severe allergies to vaccine components or other physical limitations, and a small percentage of individuals do not respond to vaccines (they don't work for these people). These people are at risk, and the only hope they have for protection is that enough people around them are immune through vaccination and therefore cannot catch and pass on the disease to them. Just as no one of us can drive safely on the freeways unless everyone follows the traffic laws, the protection of individual children and families from vaccine preventable diseases depends on a successful immunization program for the whole community.

For more information, visit the Vaccine Education Center at The Children's Hospital of Philadelphia at http://www.vaccine.chop.edu.
Another helpful source is the Immunization section of http://kidshealth.org.

Q: Is it safer to be naturally infected than immunized?
A: No! Diseases cause suffering, and in some cases permanent disability and death. Vaccines allow a person to be protected from the disease without risking the serious adverse effects of that illness. What is "natural" about a child's suffering?

Immunity from a disease may follow a single episode of infection, although this is not always true. Immunity acquired through vaccines in some cases requires several doses. However, the cost for disease-acquired protection can be high. Complications of infection with vaccine-preventable diseases can include pneumonia from chickenpox or pneumococcus, mental retardation from Hib, severe birth defects from rubella, liver cancer from hepatitis B virus, or brain damage or death from measles.

For more information on the complications and comparative risks of vaccine preventable diseases, we recommend that you link to one of these web sites for the latest research:


Many parents try to compare the risk of immunizations to the risk of disease. They say that "even one case" of adverse reaction to a vaccine is too many. To look at the real risk, we must compare the numbers. The risk of dying of complications from the measles is 1 in 1000 cases. The risk of suffering a severe adverse reaction is 1 in 1,000,000. Which risk is greater for your child?

Immunization is one of the greatest achievements of modern medicine. It has spared millions of people the effects of devastating diseases, and saves the lives of thousands each year in the United States alone. Widespread immunization is one of the most important ways to protect people of all ages against serious infectious diseases and their consequences and has nearly eliminated many diseases. Measles, diphtheria and pertussis were once responsible for millions of infections and thousands of disabilities and deaths each year. We now see very few cases of measles, almost no cases of diphtheria, and the number of pertussis cases is only a small percentage of the 175,000 cases per year reported in the 1940's.

One goal of immunization is to eliminate disease. That has been accomplished in the case of smallpox, which was responsible for 300 million deaths, more than any other disease in history. Smallpox has been eradicated worldwide through immunization. There is also a plan to eradicate polio by the year 2008.

Just a few statistics on the impact of immunizations:

Haemophilus Influenzae type b (Hib): Before 1985 Hib caused serious infections in 20,000 children a year, including meningitis (12,000 cases) and pneumonia (7,500 cases). In San Diego County there were no cases in 2000.

Because of the success of the Hib vaccine in reducing the incidence of meningitis in children under 5, the new leading cause of bacterial meningitis is the streptococcal pneumococcus bacteria. Fortunately, we now have the pneumococcal vaccine (PCV) to protect our infants and toddlers from this devastating disease.

Rubella (German measles): In the 1964-1965 epidemic, there were 12.5 million cases of rubella (German measles). Of the 20,000 infants born with congenital rubella syndrome, 11,600 were deaf, 3,580 were blind, and 1,800 were mentally retarded as a result of the infection. In 2002, there was 1 reported case in San Diego County.

Rubeola (Measles): Before 1963, when the first measles vaccine was licensed, more than 3 million cases of measles and 500 deaths from measles were reported every year in the U.S. More than 9 out of 10 children had measles disease by age 15. After the vaccine was introduced, and school immunization requirements were implemented, disease rates went down, reaching a low of 3 cases in San Diego County in 1983. The disease made a comeback in 1989-91 both nationally and locally, due to low immunization rates in preschool aged children and infants. There were 985 reported cases in San Diego during 1990, and 3 children died.

Today, largely due to air travel, we are still at risk for measles due to outbreaks in other countries. In 2003, a young adult became infected with the measles virus while in Europe then flew to San Francisco, potentially infecting individuals on the airplane and contacts in San Francisco. 2008 saw the first outbreak of measles in San Diego since 1991. Twelve cases were reported and some 70 people were quarantined at their homes to interrupt the spread of the disease.

Polio: In 1952, polio paralyzed more than 21,000 people in the U.S. The last case of polio in the Western hemisphere was reported in 1979.

Pertussis (Whooping Cough): In the early 1940s, the national average was 175,000 cases of pertussis (whooping cough) each year, resulting in the deaths of 8,000 children annually. Although much less common, this disease continues to be a problem in San Diego County. In 2003, we had 101 reported cases locally, resulting in 145 days of hospitalization which cost approximately $362,500. Also, in 2005, 371 cases of whooping cough were reported in the County, the highest number in many years.

Diphtheria: In the 1920s, there were 100,000 to 200,000 cases of diphtheria each year in the U.S. 13,000 people died from the disease. We have not seen a case in San Diego County for over 15 years, but we remain at risk because of travel to the former Soviet Union and many other countries around the world where this disease still exists.

A case of diphtheria was reported in the United States in 2003. After returning to Pennsylvania from Haiti, a 63-year-old man visited a local emergency department complaining of a sore throat and difficulty swallowing. He was treated and released. On the fourth day of illness he returned to emergency with chills, difficulty swallowing and breathing, nausea and vomiting. He was admitted to intensive care where he was eventually diagnosed with diphtheria. After several days in the hospital he developed cardiac complications and died. He had reported never being vaccinated against diphtheria.


Due to the current high levels of immunization in the United States, most of these diseases have been cut to near zero. Thanks to immunization, smallpox has been eradicated, polio has been eliminated, and only 2 cases of diphtheria, 116 cases of measles, and 3 cases of congenital rubella syndrome were reported for the whole nation in 2001.


Q: Do vaccines overload the immune system in infants or children?
A:
Many parents have a hard time watching their child get even one shot, and it can be even harder to watch their healthy baby getting multiple injections. As recently as 15 years ago children were given five shots by the time they were 2 years old, and no more than two shots at a single visit. Now children may receive as many as 26 shots by the time they are 2 years old and as many as six or seven shots in a single visit! It is natural for parents to wonder whether children can handle so many shots at the same time and whether vaccines can overwhelm the immune system.

Infants and young children daily meet and manage many challenges to their immune system all at the same time. Although the mother's womb is free from bacteria and viruses, once born, every baby immediately faces a host of different threats to the immune system. From birth, thousands of different bacteria start to live on surface of the baby's intestines. By quickly making an immune response to these bacteria, babies keep the bacteria from invading their bloodstream and causing serious disease.

Other challenges include the food they eat, and the things and people they touch. In fact, babies can respond to millions of different viruses and bacteria because they have billions of immunologic cells circulating in their bodies. So the vaccines given in the first two years of life are only a tiny part of what every infant's immune system successfully meets and overcomes every day.

Even though we know that the shots our babies are being given are important, we hate to see them cry. For useful tips on how to comfort your baby during and after immunizations, see Be There for Your Child During Shots. You can also ask your doctor or health care provider for a copy when your child is immunized.

Q: Does the MMR vaccine cause autism?
A: Many carefully performed studies say no. For the latest information on this topic, please see the sources listed below:

American Academy of Pediatrics (AAP)’s web pages with information about vaccines and autism:

http://www.aap.org/new/autisminfomain.html


The federal Centers for Disease Control and Prevention has a wealth of information on vaccine safety:

http://www.cdc.gov/vaccinesafety/concerns/

Also, please see the Statement on Vaccines and Autism From The Public Health Officer


Q: How can I sort out the conflicting information about vaccines? How do I know if the information about vaccines that I find on the Web is accurate?
A: With the large amount of information on the internet now, it can be confusing to determine what is accurate and valid information. The National Network for Immunization Information has a good answer to this question. You can find it here:


http://www.immunizationinfo.org/parents/evaluatingWeb.cfm

Also, the Centers for Disease Control and Prevent has more information here:

http://www.cdc.gov/vaccines/vac-gen/evalwebs.htm


Most importantly, the health information that you find on the web should be discussed with your doctor or health professional. Information from the web should add to rather than replace the information or advice given to you by your doctor.



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