Chickenpox
(Varicella)
Chickenpox
is an infection caused by the varicella virus, and is highly contagious.
The rash begins as red bumps that turn into blisters and cover the
entire body. There are usually as many as 300-500 blisters during
a single infection.
The varicella
vaccine is given to prevent chickenpox and the severe, and occasionally
fatal, consequences of chickenpox. These can include severe infection
of the skin, swelling of the brain, and pneumonia (usually more
severe in children 13 or older and adults).
Chickenpox vaccine
should be given to children who have not had chickenpox disease.
One dose of the vaccine is given to children between 12 months and
12 years of age. Two doses, separated by four to eight weeks, are
needed by children 13 to 18 years of age.
For the most
up to date information about chickenpox (Varicella) and the Varicella
vaccine:
Children's
Hospital of Philadelphia: Vaccines at a Glance
CDC: Vaccine Information Statement
CDC: Vaccine Information
FAQ's about Chickenpox
Diphtheria
Diphtheria
is a respiratory disease caused by bacteria. It is spread by coughing
and sneezing. The toxin released by the bacterium causes difficulty
breathing and swallowing. It also attacks the heart, kidneys, and
nervous system. It can lead to airway obstruction, coma, and death
if not treated. In the 1920s, diphtheria was a common cause of death
in children and adolescents. At its peak, about 150,000 cases of
diphtheria occurred in the United States every year! The diphtheria
vaccine, first used in the United States in the early 1940s, has
virtually eliminated the disease. Now we see less than 2 cases a
year in the U.S. Diphtheria toxoid (contained in DTP, DTaP, DT or
Td vaccines) can prevent this disease.
There are nations
still having outbreaks of diphtheria. It is important to check the
"Travelers Health" website of the National Center for
Infectious Diseases for up-to-date information on your destinations
before you travel.
For the most
up to date information about diphtheria and the DTP/DTaP/DT/Td vaccine:
Children's
Hospital of Philadelphia: Vaccines at a Glance
CDC:
Vaccine Information Statement
CDC: Vaccine Information
Haemophilus
influenzae type b (Hib)
The bacteria
Haemophilus influenzae type b (or Hib) is a severe bacterial infection,
occurring primarily in infants. It can cause meningitis, bloodstream
infections, arthritis, bone infections, skin and throat infections,
pneumonia and other diseases.
Children with meningitis often have fever, stiff neck, and drowsiness.
Symptoms can progress to include coma and death. Some children recover
from the disease but are left permanently paralyzed, deaf, or mentally
retarded. This disease can be serious in children under age 1, but
there is little risk of getting the disease after age 5. Hib meningitis
causes death in one out of 20 children. It is spread by coughing
and sneezing. Although the Hib vaccine prevents what was once the
most common cause of bacterial meningitis, it does not prevent all
causes of meningitis. Other causes of meningitis include pneumococcus
and meningococcus. To date, there is no routinely recommended vaccine
to fight meningococcus. However, there is now a pneumococcal vaccine.
For the most
up to date information about Hib and the Hib vaccine:
Children's
Hospital of Philadelphia: Vaccines at a Glance
CDC:
Vaccine Information Statement
CDC: Vaccine Information
Hepatitis
A
Hepatitis
A is a virus that causes disease of the liver. Symptoms include
tiredness, fever, jaundice (a yellowing of the skin), nausea, loss
of appetite and vomiting. Young children are much less likely to
develop symptoms when they are infected with hepatitis A virus so
the disease is often not recognized until the child's caregiver
becomes ill with hepatitis A. The hepatitis A virus is found in
the stools of infected people. You can catch the virus in a number
of ways:
If you are changing
a diaper that is contaminated with the virus, you are likely to
get infected if you don't carefully scrub your hands with soap and
water.
In countries
with sewage and water problems, the virus can enter the water supply
and contaminate anything that comes in contact with the water. So
if you are travelling to a country where hepatitis A virus infections
are common you should avoid the following:
- ice and unbottled
water
- uncooked
shellfish
- uncooked
or unpeeled vegetables and fruit from street vendors
- salads
The hepatitis
A vaccine is recommended for all children living in areas of the
United States where the incidence of hepatitis A virus infections
is at least twice the national average. California is one of these
high-risk states. Others include Arizona, Alaska, Idaho, Nevada,
New Mexico, Oklahoma, Oregon, South Dakota, Utah, and Washington.
For the most
up to date information about hepatitis A and the hep A vaccine:
Children's
Hospital of Philadelphia: Vaccines at a Glance
CDC:
Vaccine Information Statement
CDC: Vaccine Information
Hepatitis
B
Hepatitis
B is a serious public health problem that affects people of all
ages in the United States and around the world. Each year, more
than 240,000 people contract hepatitis B in the United States. The
Hep B virus attacks the liver and can lead to severe illness, liver
damage, and, in some cases, death. The best way to be protected
from hepatitis B is to be vaccinated with hepatitis B vaccine, which
has been proven safe and effective.
Are you at risk?
About five percent of people in the U.S. will get hepatitis B sometime
during their lives. Certain behaviors make your risk for hepatitis
B much higher. You may be at risk for hepatitis B if you:
- have a job
that exposes you to human blood
- share a household
with someone who has lifelong HBV infection
- inject drugs
- have sex
with a person infected with HBV
- have sex
with more than one partner during a six-month period
- received
blood transfusions in the past before excellent testing was available
(1975)
- have hemophilia
- are a patient
or worker in an institution for the developmentally disabled
- are an inmate
of a long-term correctional facility
- travel internationally
to areas with a high prevalence of hepatitis B
Hepatitis B is more prevalent in some parts of the world. You may
be at higher risk of contracting hep B if you:
- were born
in Asia, Africa, the Amazon Basin in South America, the Pacific
Islands, Eastern Europe, or the Middle East
- are a person
whose parents were born in an area listed above
- were adopted
from an area listed above
- are an Alaska
native
Hepatitis B
virus can be spread by:
- unprotected
sex
- injecting
drug use
- during birth
from mother to child
- contact with
blood or open sores of an infected person
- human bites
- sharing a
household with an infected person
- sharing items
such as razors, toothbrushes, or washcloths
- pre-chewing
food for babies or sharing chewing gum
- using unsterilized
needles in ear or body piercing, tattooing, or acupuncture
- using the
same immunization needle on more than one person
Hepatitis B
virus IS NOT spread by:
- casual contact
like holding hands
- eating food
prepared by a carrier (unlike hep A)
- kissing on
the cheek or dry lip kissing
- sharing silverware,
plates, or cups
- visiting
an infected person's home
- playing with
a child who is a carrier
- sneezing
or coughing
Most people
who get hepatitis B as babies or children don't look or feel sick
at all. Similarly, over half of adults who get hepatitis B never
have any symptoms or signs of the disease. When they get the blood
test results indicating they've had or have the disease many are
taken by surprise. If people do have signs or symptoms, they may
experience any or all of the following:
- loss of
appetite
- yellow skin
and eyes (jaundice)
- nausea, vomiting
- fever
- weakness,
tiredness, inability to work for weeks or months
- abdominal
pain and/or joint pain
- dark urine
For the most
up to date information about hepatitis B:
Immunization Action Colaition
Children's
Hospital of Philadelphia: Vaccines at a Glance
CDC:
Vaccine Information Statement
CDC: Vaccine Information
Measles
Measles
is a respiratory disease that is caused by a virus. It is spread
by coughing and sneezing and is highly contagious. The measles virus
causes high fever, cough, runny nose, red watery eyes and a red,
pinpoint rash that starts on the face and spreads to the rest of
the body. The rash lasts about a week. However, the virus can also
cause pneumonia, a consequence that can lead to death. Although
some people don't think of pneumonia as a consequence of measles,
it is actually quite common. Some older children infected with the
virus suffer from encephalitis (an infection of the brain), which,
in many cases, causes permanent brain damage.
For the most
up to date information about measles and the MMR vaccine:
Children's
Hospital of Philadelphia: Vaccines at a Glance
CDC:
Vaccine Information Statement
CDC: Vaccine Information
Mumps
Mumps is caused by a virus and usually causes swelling in the salivary
or parotid glands, just below the ear, lasting for seven days. The
chipmunk-like appearance of people infected with mumps is how mumps
got its name. Mumps can cause meningitis, inflammation of the testicles
or ovaries, inflammation of the pancreas and permanent deafness.
Several hundred cases of mumps are still reported in the United
States every year.
For the most
up to date information about mumps and the MMR vaccine:
Children's
Hospital of Philadelphia: Vaccines at a Glance
CDC:
Vaccine Information Statement
CDC: Vaccine Information
Polio
Polio is caused by a virus and is very contagious. It affects people
differently - some don't feel sick at all, others complain of sore
throat, fever, stomach pain or vomiting, stiff neck or headache.
The virus does its damage by first reproducing itself in the intestines,
then traveling through the bloodstream where it can infect the brain
and spinal cord. The paralysis associated with polio occurs when
the virus replicates and attacks the nervous system. Only about
one in ten people who were paralyzed by polio recovered - most were
confined to wheelchairs or iron lungs for the rest of their lives.
Through a continuing global effort, the plan is to eradicate polio
by the year 2008. The Western Hemisphere was declared polio free
in 1991. However, due to international travel, the virus has been
imported on a few different occasions from countries that still
suffer from the disease.
The inactivated
polio vaccine (or IPV) is now the only vaccine given in the United
States to prevent polio, while previously OPV or polio drops were
used. The advantage of the OPV was that it was almost 100 percent
effective in preventing polio. Because the live virus was present
in the stool of the vaccinated person, about 25 percent of people
who came in contact with someone who was immunized, would also be
immunized (this is called contact immunity). This helped to raise
levels of protection against polio in our community. However, despite
OPV's 40 years of success, there was an extremely rare but very
dangerous side effect: permanent paralysis. Paralysis caused by
OPV occurred in about 1 of every 750,000 first doses of the vaccine.
The IPV form, now recommended by the Centers for Disease Control
and Prevention (CDC) and the American Academy of Pediatrics (AAP),
does not, and cannot cause paralysis.
For the most
up to date information about polio and the Polio vaccine:
Children's
Hospital of Philadelphia: Vaccines at a Glance
CDC:
Vaccine Information Statement
CDC: Vaccine Information
Pertussis
Pertussis
(or whooping cough) is one of the most contagious diseases around.
Caused by a bacterium, whooping cough makes children cough uncontrollably.
With the cough so hard and so persistent children have trouble catching
their breath. Imagine having coughing fits over a minute and trying
to get air through your windpipe when it is severely narrowed by
mucus! It can be very frightening. Severe pneumonia or seizures
can also develop from this disease.
Pertussis is
an unusual childhood disease in that children don't usually catch
it from other children. Rather, pertussis is a common cause of disease
in adolescents and young adults, and young children often catch
it from an adult living in the home. If you have ever had a cough
illness that lasted about 3 weeks, it could have been pertussis.
Remember that this disease is much more serious for infants and
can lead to encephalitis (due to lack of oxygen) and even death.
For the most
up to date information about pertussis and the DTP/DTaP vaccine:
Children's
Hospital of Philadelphia: Vaccines at a Glance
CDC:
Vaccine Information Statement
CDC: Vaccine Information
Rubella (German
Measles)
Rubella
is respiratory disease caused by a virus and is also known as German
measles. It causes a mild rash on the face, swelling of glands behind
the ear, occasionally a short-lived swelling of small joints (like
the joints of the hand), and low-grade fever. It tends to be a mild
disease in children and young adults. But not always! In the year
before vaccination started, 20,000 babies were born with birth defects
because of rubella's capacity to damage the developing child. If
a woman is infected with rubella in the first trimester of her pregnancy,
the chance that the unborn child will be permanently harmed by the
virus is about 85 percent! Rubella virus causes blindness, deafness,
heart defects or mental retardation.
Rubella vaccine
is a unique example of vaccinating one person to protect another.
We vaccinate girls so that, if they become pregnant as adults, their
unborn children will be protected against the devastating effects
of rubella virus. We vaccinate boys to help stop the spread of rubella
in the community.
For the most
up to date information about rubella and the MMR vaccine:
Children's
Hospital of Philadelphia: Vaccines at a Glance
CDC:
Vaccine Information Statement
CDC: Vaccine Information
Tetanus
Tetanus is a disease caused by a harmful protein called a toxin.
This toxin attacks the muscles and causes them to painfully constrict.
If the toxin affects the muscles of the throat, breathing can be
so difficult that the child will suffocate. Tetanus is different
from other vaccine preventable diseases because it is not a disease
that you catch from someone else. The bacteria live in the soil
and usually enter the body following puncture of the skin. Items
likely to be contaminated with the tetanus bacteria include nails
or pieces of glass that were lying on the ground. Also, gardening
is an activity that exposes people to tetanus. Once under the skin,
the bacteria make a toxin that causes muscle spasms. If these spasms
occur in the throat, they can interfere with breathing, causing
suffocation. In addition, the toxin can also damage the heart. It's
part of children's nature to play and be adventurous and as they
can often injure themselves, it's important to immunize them against
tetanus. Hand washing and bathing do little once the bacteria actually
get under the skin.
Although tetanus
bacteria are everywhere, tetanus is an uncommon cause of disease
in the United States. But it's not as rare as you may think. As
many as 70 cases of tetanus causing about 15 deaths are reported.
For the most
up to date information about tetanus and the DTP/DTaP/DT/Td vaccine:
Children's
Hospital of Philadelphia: Vaccines at a Glance
CDC:
Vaccine Information Statement
CDC: Vaccine Information
Pneumococcal
Disease
Pneumococcus
is a bacteria that is commonly found lining the surface of the nose
and the back of the throat. This bacteria can cause pneumonia, meningitis,
bloodstream infections, and ear infections. Much like Haemophilus
influenzae type b (Hib), the pneumococcus bacteria affects the most
defenseless of our population, infants and toddlers. Thousands of
children die each year, or are permanently damaged due to diseases
caused by pneumococcus. The reason that infants and young children
are at greatest risk of serious infection is that they are unable
to develop immunity to the sugar (or polysaccharide) that coats
the bacteria, something that older children do naturally over time.
Because most adults have immunity to pneumococcus, a mother will
passively transfer antibodies from her own blood to the blood of
her baby before the baby is born. The antibodies that the baby gets
from her mother usually last for a few months. However, after that
time, the baby is unprotected. Often, children who were previously
healthy and well-nourished can suffer permanent disabilities or
death.
The risk of
pneumococcal infection is even greater for children less than 5
years of age with the following conditions:
- Children
without spleens
- Children
infected with HIV, the virus that causes AIDS
- Children
with sickle cell disease
- Children
who attend group child-care (defined as spending more than 4 hours
a week with at least 2 other children [non-relatives] under adult
supervision)
- Children
who are of Alaskan Native, American Indian, or African American
descent
- Children
with long-term illnesses or those who have weakened immune systems
caused by specific diseases (such as AIDS) or the treatment of
certain diseases (such as cancer).
For the most
up to date information on pneumococcal and the PCV7 vaccine:
Children's
Hospital of Philadelphia: Vaccines at a Glance
CDC:
Vaccine Information Statement
CDC: Vaccine Information
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